Fatality rate was obviously higher among COVID-+19 patients with AKI than those without AKI ( RR=7.08, P<0.001). Among 56 COVID-19 patients with AKI, 33.9% were died on mean 10.9 day after hospitalization. By multivariate logistic regression, male, older age and comorbidity with diabetes were three important independent risk factors predicting AKI among COVID-19 patients. Although AKI was more common in critical ill patients with COVID-19, there was no significant association between oxygenation index and renal functional indices among COVID-19 patients with AKI. On admission, 56 (15.8%) patients were with AKI. Of 355 COVID-19 patients, common, severe and critical ill cases accounted for 63.1%, 16.9% and 20.0%, respectively. Patient’s prognosis was tracked and risk factors of AKI was analyzed. Three-hundred and fifty-five COVID-19 patients with were recruited and clinical data were collected from electronic medical records.
This study described acute kidney injury (AKI) at early stage of COVID-19 and its clinical significance. Coronavirus disease 2019 (COVID-19) is a newly emerged infection of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) and has been pandemic all over the world.
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